Anti-CCDN2AIP/CARF Antilichaam Picoband® 31.0550 Vervoeging

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of DNA-binding transcription factor activity. Located in granular component. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and skeletal muscle tissue. Orthologous to human CARF (calcium responsive transcription factor) .

Carf; Als2cr8; Calcium-responsive transcription factor; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium-response factor; CaRF

Carf

241066

Q8VHI4

Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived mouse CDKN2AIP/CARF recombinant protein (Position: R183-T689) . Human CDKN2AIP/CARF shares 78.3% and 88.1% amino acid (aa) sequence identity with human and rat CDKN2AIP/CARF, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Tao, X., West, A. E., Chen, W. G., Corfas, G., Greenberg, M. E. A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF. Neuron 33: 383-395, 2002.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

61 kDa

6

Calcium response factor

Calcium-responsive transcription factor

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.