Anti-CCRN4L NOCT Antilichaam

Boster Bio Anti-CCRN4L NOCT Antibody catalog # A10951. Tested in WB applications. This antibody reacts with Human, Rat.

Nocturnin

NOCT

Q9UK39

Human, Rat

A synthetic peptide corresponding to residues in Human CCRN4L

Adipose tissue. Expression is higher in subcutaneous adipose tissue as compared to visceral adipose tissue.

WB

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Circadian deadenylase which plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Degrades poly (A) tails of specific target mRNAs leading to their degradation and suppression of translation. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. Plays an important role in favoring adipogenesis over osteoblastogenesis and acts as a key regulator of the adipogenesis/osteogenesis balance. Promotes adipogenesis by activating PPARG transcriptional activity in a deadenylase- independent manner by facilitating its nuclear translocation. Regulates circadian expression of NOS2 in the liver and negatively regulates the circadian expression of IGF1 in the bone. Critical for proper development of early embryos (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A10951

48196 MW

WB: 1:500-1:1000

Nocturnin

Cytoplasm . Nucleus . Cytoplasm, perinuclear region .

Nocturnin

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2