Anti-CD147/Emmprin/Basigin (extracellulair gebied) Antilichaam

D147 (Basigin/EMMPRIN) is a type I integral membrane receptor protein belonging to the immunoglobulin superfamily. CD147 is a glycosylated protein with four known isoforms with isoform 2 being the most abundantly expressed. In many cancers, CD147 is overexpressed and stimulates the secretion of extracellular matrix metalloproteinases by tumor fibroblasts, which can promote tumor progression. CD147 is co-expressed with the amino acid transporter, CD98h, in metabolically active cells such as lymphocytes, macrophages, and tumor cells. CD147 interaction with caveolin and cyclophilins regulates its functions, and this protein may function outside of tumor cells through cell shedding and microvesicle release.

Our CD147/Emmprin/Basigin (Extracellular region) mouse monoclonal primary antibody from PhosphoSolutions is produced in-house. It detects human CD147/Emmprin/Basigin (Extracellular region) and is protein g purified. It is great for use in ELISA, WB, ICC, IP.

Our CD147/Emmprin/Basigin (Extracellular region) mouse monoclonal primary antibody from PhosphoSolutions is produced in-house. It detects human CD147/Emmprin/Basigin (Extracellular region) and is Protein G purified. It is great for use in WB, ICC, IP.

Basigin, 5F7, Collagenase stimulatory factor Extracellular matrix metalloproteinase, EMMPRIN, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF, CD147, BSG

CD147

P35613

Human

Clone (M036) was generated from a proprietary antigen related to the native human CD147 expressed in NCI-H1915 lung cancer cell line.

CD147/Emmprin/Basigin (Extracellular region)

M036

Unconjugated

ELISA, WB, ICC, IP

Cell Adhesion Molecules, Immunology, Oncoproteins

Protein G Purified

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

GOmAb

38-58

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Blue Ice

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Protein G purified culture supernatant.

1:2000

1:100

Clone M036 mouse monoclonal antibody detects a 38-58 kDa* protein on SDS-PAGE immunoblots of human BEAS, NCIH28, NCI-H1299, LNCaP, and A431 cells, as well as human brain tissues. The antibody works for western blot, immunoprecipitation, ELISA capture, and immunocytochemistry.

1:100

Western blots performed on each lot.

Mouse

Liquid

IgG2a

Human

Quality Control: WB

AB_3068384