Anti-CD18 / Integrine beta-2 (ITGB2) Monoklonale Antilichaam (Kloon: 68-5A5)

Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Beta 2 (antigen CD18 (p95) ; CD18; Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta; Cell surface adhesion glycoproteins LFA-1/CR3/p150; Complement component 3 receptor 3 and 4 subunit; Complement receptor C3 beta subunit; Integrin beta-2 (ITGB2) ; LAD; LCAMB; Leukocyte Cell Adhesion

ITGB2

3689

P05107

Human

Stimulated human leukocytes

68-5A5

Functional Assay, FACS, IF

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Functional Studies (Order Ab without Azide) ; Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)

Mouse IgG2a, kappa