Anti-CD357 / GITR Monoklonale Antilichaam (Kloon: GITR/1585)

The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals throμgh protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.

Activation inducible TNFR family receptor; AITR; GITRD; Glucocorticoid induced TNFR related protein; Glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation inducible protein; TNFRSF18

TNFRSF18

8784

Q9Y5U5

Human

Human full-length TNFRSF18 protein

GITR/1585

ELISA

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

ELISA (For coating, order Ab without BSA & Azide)

Mouse IgG3, kappa