Anti-CD62L (L-selectine) Monoklonale Antilichaam (Kloon: LAM1-116)

Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.

A.11; AI528707; CD62 antigen ligand; CD62L; gp90-MEL; IgA nephropathy, susceptibility to, included; L Selectin; L-selectin; LAM1; LECAM1; LEU8; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; Lnhr; LSEL; Ly-22; LYAM1; Lymph node homing receptor; Lymphocyte antigen 22

SELL

6402

P14151

Human

MAb raised against supernatant from phorbol myristic acid activated human peripheral blood leukocytes.

LAM1-116

ELISA, FACS, WB

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

ELISA (For coating, order antibody without BSA) ; Flow Cytometry (1-2ug/million cells) ; Western Blot (1-2ug/ml)

Mouse IgG1, kappa