Anti-CD71 / Transferrin Receptor (TFRC) Monoklonale Antilichaam (Kloon: 66IG10) -CF488

It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

TFRC

7037

P02786

Human

Human thymocytes (T-cells)

66IG10

FACS, IF

Antibody Purified from Bioreactor Concentrate by Protein A/G and conjμgated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format.

Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous.

Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood) ; Immunofluorescence (1:50-1:100)

Mouse IgG1, kappa

CF488