Anti-CD9 Antibody Picoband®

CD9 antigen is a protein that in humans is encoded by the CD9 gene. CD9 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is found on the surface of exosomes. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. This protein also seems to be a key part in the egg-sperm fusion during mammalian fertilization. While oocytes are ovulated, CD9-deficient oocytes are not properly fused with sperm upon fertilization. CD9 is located in the microvillar membrane of the oocytes and also appears to intervene in maintaining the normal shape of oocyte microvilli.

Boster Bio Anti-CD9 Antibody Picoband® catalog # A01202-2. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Microtubule-associated protein 2; MAP-2; MAP2

CD9

928

P21926

Human

No cross-reactivity with other proteins.

E.coli-derived human CD9 recombinant protein (Position: Q139-K192) .

ELISA, Flow Cytometry, IF, IHC, WB

Cell Type Marker, Cytoskeleton, Cytoskeleton/ECM, Microtubules, Neural Stem Cells, Neuron Marker, Neuroscience, Signal Transduction, Stem Cells

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

1. Katz F, Povey S, Parkar M, Schneider C, Sutherland R, Stanley K, Solomon E, Greaves M (March 1984) . Chromosome assignment of monoclonal antibody-defined determinants on human leukemic cells. Eur J Immunol 13 (12) : 1008–1013. 2. Le Naour F, Rubinstein E, Jasmin C, Prenant M, Boucheix C (2000) . Severely Reduced Female Fertility in CD9-Deficient Mice. Science 287 (5451) : 319–321. 3. Runge KE, Evans JE, He ZY, Gupta S, McDonald KL, Stahlberg H, Primakoff P, Myles DG (2007) . Oocyte CD9 is enriched on the microvillar membrane and required for normal microvillar shape and distribution.Developmental Biology 304 (1) : 317–325.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A01202-2

22 kDa

6

Microtubule-associated protein 2

Cytoplasm, cytoskeleton. Cell projection, dendrite.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.