Anti-Cdc27/APC3 Konijn Monoklonale Antilichaam

Boster Bio Anti-Cdc27/APC3 Rabbit Monoclonal Antibody catalog # M03905. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Cell division cycle protein 27 homolog; Anaphase-promoting complex subunit 3; APC3; CDC27 homolog; CDC27Hs; H-NUC; CDC27; ANAPC3, D0S1430E, D17S978E

CDC27

996

P30260

Human, Mouse, Rat

A synthesized peptide derived from human Cdc27/APC3

Clone: IOB-3

Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement. .

WB

Cell Biology, Cell Cycle, Cell Division, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Spindle

Affinity-chromatography

0.5mg/ml

Liquid

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M03905

91867 MW

35 kDa

Cell division cycle protein 27 homolog

Nucleus.

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.