Anti-Cdk2 Antibody Picoband® (monoklonale, 5B12D1)

CDK2, Cyclin-Dependent Kinase2, is also known as P33. The CDK2 protein was highly homologous to p34 (CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that CDK2 is the human homolog of Eg1. The CDK2 gene is mapped to 12q13, the same region to which the CDK4 gene maps. Human cyclin A binds independently to 2 kinases, p34 (cdc2) or p33. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/cyclin A but not with p34 (cdc2) /cyclin A. The gene for p33 shares 65% sequence identity with p34 (cdc2) . P33 (cdk2) plays a unique role in cell cycle regulation of vertebrate cells.

Boster Bio Anti-Cdk2 Antibody Picoband® (monoclonal, 5B12D1) catalog # M00166-3. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Solute carrier family 2, facilitated glucose transporter member 1; Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporter; SLC2A1; GLUT1

CDK2

1017

P24941

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human Cdk2 recombinant protein (Position: E81-L298) . Human Cdk2 shares 98.6% amino acid (aa) sequence identity with rat Cdk2.

Clone: 5B12D1

Detected in erythrocytes (at protein level) . Expressed at variable levels in many human tissues.

Flow Cytometry, IHC, WB

Channels, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Plasma Membrane, Signal Transduction

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.

1. Demetrick, D. J., Zhang, H., Beach, D. H.Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes.Cytogenet. Cell Genet. 66: 72-74, 1994. 2. Tsai, L.-H., Harlow, E., Meyerson, M.Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated P33 kinase.Nature 353: 174-177, 1991.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=M00166-3

46659 MW

30 kDa

6

Solute carrier family 2 (facilitated glucose transporter), member 1

Cell membrane. Multi-pass membrane protein. Melanosome.

Isocitrate dehydrogenase [NADP] cytoplasmic

Mouse IgG2a

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.