Anti-CEP110/CNTRL Antilichaam Picoband® 31.0647 Vervoeging

Centriolin is a protein that in humans is encoded by the CNTRL gene. It was previously known as CEP110. This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centrosomal protein 1.

CNTRL; CEP1; CEP110; Centriolin; Centrosomal protein 1; Centrosomal protein of 110 kDa; Cep110

CNTRL

11064

Q7Z7A1

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human CEP110/CNTRL recombinant protein (Position: T991-E2187) .

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Guasch, G., Mack, G. J., Popovici, C., Dastugue, N., Birnbaum, D., Rattner, J. B., Pebusque, M.-J. FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t (8;9) (p12; q33) . Blood 95: 1788-1796, 2000. 2. Ou, Y. Y., Mack, G. J., Zhang, M., Rattner, J. B. CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation. J. Cell Sci. 115: 1825-1835, 2002. 3. Popovici, C., Mattei, M.-G., Rattner, J. B., Birnbaum, D., Pebusque, M.-J. Assignment of the centrosomal protein 110 gene (Cep110) to mouse chromosome bands 2B-C1 by in situ hybridization. Cytogenet. Cell Genet. 89: 216-217, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

269 kDa

6

Centriolin

Centriolin

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.