Anti-CHP2 Antibody Picoband® APC-vervoeging

This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988) . This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520.

CHP2; HCA520; Calcineurin B homologous protein 2; Hepatocellular carcinoma-associated antigen 520

CHP2

63928

O43745

Human

No cross-reactivity with other proteins

E.coli-derived human CHP2 recombinant protein (Position: M1-K196) . Human CHP2 shares 81.6% amino acid (aa) sequence identity with both mouse and rat CHP2.

Flow Cytometry

Immunogen affinity purified.

Liquid

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

22 kDa

6

Calcineurin like EF-hand protein 2

Calcineurin B homologous protein 2

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.