Anti-CLTB Antibody Picoband® 0,00647 Vervoeging

Clathrin, light chain B is a protein in humans that is encoded by the CLTB gene. Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.

CLTB; Clathrin light chain B; Lcb

CLTB

1212

P09497

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence in the middle region of human CLTB, identical to the related mouse and rat sequences.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Brodsky, F. M., Galloway, C. J., Blank, G. S., Jackson, A. P., Seow, H.-F., Drickamer, K., Parham, P. Localization of clathrin light-chain sequences mediating heavy-chain binding and coated vesicle diversity. Nature 326: 203-205, 1987. 2. Gross, M. B. Personal Communication. Baltimore, Md. 4/20/2011. 3. Jackson, A. P., Parham, P. Structure of human clathrin light chains: conservation of light chain polymorphism in three mammalian species. J. Biol. Chem. 263: 16688-16695, 1988.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

25 kDa

6

Clathrin light chain B

Clathrin light chain B

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.