Anti-collageen I/COL1A1 Antibody Picoband® 0,00647 Vervoeging

Pro-alpha1 chains of type I collagen

Collagen alpha-1 (I) chain; Alpha-1 type I collagen; COL1A1

COL1A1

1277

P02452

Human, Mouse

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen I, different from the related rat and mouse sequences by two amino acids.

Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.

Flow Cytometry

Cell Biology, Cell Cycle, Epigenetics and Nuclear Signaling, Kinases/Phosphatases

Immunogen affinity purified.

Liquid

Type I collagen is a member of group I collagen (fibrillar forming collagen) .

1. Aihara, M., Lindsey, J. D., Weinreb, R. N. Ocular hypertension in mice with a targeted type I collagen mutation. Invest. Ophthal. Vis. Sci. 44: 1581-1585, 2003. 2. Cabral, W. A., Makareeva, E., Colige, A., Letocha, A. D., Ty, J. M., Yeowell, H. N., Pals, G., Leikin, S., Marini, J. C. Mutations near amino end of alpha-1 (I) collagen cause combined osteogenesis imperfecta/Ehlers-Danlos syndrome by interference with N-propeptide processing. J. Biol. Chem. 280: 19259-19269, 2005.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

138941 MW

No cross reactivity with other proteins.

6

Collagen alpha-1 (I) chain

Secreted, extracellular space, extracellular matrix .

Belongs to the fibrillar collagen family.

Collagen alpha-1 (I) chain

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.