Anti-collageen I/COL1A1 Antibody Picoband®

Pro-alpha1 chains of type I collagen

Anti-Collagen

Collagen alpha-1 (I) chain; Alpha-1 type I collagen; Col1a1; Cola1

COL1A1

12842

P11087

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of mouse Collagen I, identical to the related rat sequence, and different from the related human sequence by two amino acids.

Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.

IF, IHC, ICC, WB

Collagen, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Mesenchymal Stem Cells, Signal Transduction, Stem Cells

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Type I collagen is a member of group I collagen (fibrillar forming collagen) .

1. Aihara, M., Lindsey, J. D., Weinreb, R. N. Ocular hypertension in mice with a targeted type I collagen mutation. Invest. Ophthal. Vis. Sci. 44: 1581-1585, 2003. 2. Cabral, W. A., Makareeva, E., Colige, A., Letocha, A. D., Ty, J. M., Yeowell, H. N., Pals, G., Leikin, S., Marini, J. C. Mutations near amino end of alpha-1 (I) collagen cause combined osteogenesis imperfecta/Ehlers-Danlos syndrome by interference with N-propeptide processing. J. Biol. Chem. 280: 19259-19269, 2005.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=PA2140-2

138032 MW

130 kDa, 220 kDa

No cross reactivity with other proteins.

Collagen alpha-1 (I) chain

Secreted, extracellular space, extracellular matrix .

Belongs to the fibrillar collagen family.

Collagen alpha-1 (I) chain

Rabbit IgG

Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.