Anti-COX6B1 Antilichaam (N-term)

Connects the two COX monomers into the physiological dimeric form (By similarity) .

Boster Bio Anti-COX6B1 Antibody (N-term) (Catalog # A10285-1) . Tested in IF, WB application (s) . This antibody reacts with Human.

Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1, COX6B1, COX6B

COX6B1

P14854

Human

This COX6B1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 8-22 amino acids from the N-terminal region of human COX6B1.

IF, WB

Cancer, Metabolism, Signal Transduction, Mitochondria

This antibody is purified through a protein A column, followed by peptide affinity purification.

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU (A) ) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU (B) ) . The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A10285-1

10192 Da

Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side

Monkey, Mouse

Rabbit IgG

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.