Anti-CPT1B Antibody Picoband® 0,00647 Vervoeging

CPT1B is located on 22q13.33. The protein encoded by this gene, a member of the carnitine/ choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.

Non-homologous end-joining factor 1; Protein cernunnos; XRCC4-like factor; NHEJ1; XLF

CPT1B

1375

Q92523

Human, Mouse, Rat, Monkey

No cross-reactivity with other proteins.

E.coli-derived human CPT1B recombinant protein (Position: R180-S772) .

Widely expressed.

Flow Cytometry

Cell Biology, Cell Type Markers, Developmental Biology, Reproduction, Tags & Cell Markers

Immunogen affinity purified.

Liquid

DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V (D) J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary. Binds DNA in a length-dependent manner.

1. Auinger A; Rubin D; Sabandal M; Helwig U; Rüther A; Schreiber S; Foelsch UR; Döring F; Schrezenmeir J. “A common haplotype of carnitine palmitoyltransferase 1b is associated with the metabolic syndrome”. Br J Nutr, 2013 Mar 14.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

75187 MW

6

Non-homologous end joining factor 1

Nucleus.

Segment polarity protein dishevelled homolog DVL-1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.