Anti-CRABP1 Antibody Picoband®

Cellular retinoic acid-binding protein 1 is a protein that in humans is encoded by the CRABP1 gene. This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-ed differentiation in epithelial tissue.

Boster Bio Anti-CRABP1 Antibody Picoband® catalog # A07951-1. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

DAZ-associated protein 1; Deleted in azoospermia-associated protein 1; DAZAP1

CRABP1

1381

P29762

Human

No cross-reactivity with other proteins.

E.coli-derived human CRABP1 recombinant protein (Position: R60-E118) .

Mainly expressed in testis. Expressed to a lower level in thymus. Weakly or not expressed in heart, liver, brain, placenta, lung, skeletal muscle, kidney and pancreas.

WB, Flow Cytometry, ELISA

Cancer, Cell Biology, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Oxidative Stress, Pathways and Processes, Redox Metabolism, Signal Transduction

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

RNA-binding protein, which may be required during spermatogenesis.

1. Flagiello, D., Apiou, F., Gibaud, A., Poupon, M. F., Dutirllaux, B., Malfoy, B. Assignment of the genes for cellular retinoic acid binding protein 1 (CRABP1) and 2 (CRABP2) to human chromosome band 15q24 and 1q21.3, respectively, by in situ hybridization. Cytogenet. Cell Genet. 76: 17-18, 1997. 2. Geurts van Kessel, A., de Leeuw, H., Dekker, E. J., Rijks, L., Spurr, N., Ledbetter, D., Kootwijk, E., Vaessen, M. J. Localization of the cellular retinoic acid binding protein (CRABP) gene relative to the acute promyelocytic leukemia-associated breakpoint on human chromosome 15. Hum. Genet. 87: 201-204, 1991. 3. Guidez, F., Parks, S., Wong, H., Jovanovic, J. V., Mays, A., Gilkes, A. F., Mills, K. I., Guillemin, M.-C., Hobbs, R. M., Pandolfi, P. P., de The, H., Solomon, E., Grimwade, D. RAR-alpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t (11;17) acute promyelocytic leukemia. Proc. Nat. Acad. Sci. 104: 18694-18699, 2007.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A07951-1

49229 MW

16 kDa

6

DAZ associated protein 1

Nucleus. Cytoplasm.

Chromaffin granule amine transporter

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.