Anti-CREB3L2 Antibody Picoband® PE Vervoeging

This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene.

CREB3L2; BBF2H7; Cyclic AMP-responsive element-binding protein 3-like protein 2; cAMP-responsive element-binding protein 3-like protein 2; BBF2 human homolog on chromosome 7 [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2]

CREB3L2

64764

Q70SY1

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the N-terminus of human CREB3L2, which shares 95.7% and 100% amino acid (aa) sequence identity with mouse and rat CREB3L2, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Bejarano, P. A., Padhya, T. A., Smith, R., Blough, R., Devitt, J. J., Gluckman, J. L. Hyalinizing spindle cell tumor with giant rosettes--a soft tissue tumor with mesenchymal and neuroendocrine features: an immunohistochemical, ultrastructural, and cytogenetic analysis. Arch. Path. Lab. Med. 124: 1179-1184, 2000. 2. Panagopoulos, I., Storlazzi, C. T., Fletcher, C. D. M., Fletcher, J. A., Nascimento, A., Domanski, H. A., Wejde, J., Brosjo, O., Rydholm, A., Isaksson, M., Mandahl, N., Mertens, F. The chimeric FUS/CREB3L2 gene is specific for low-grade fibromyxoid sarcoma. Genes Chromosomes Cancer 40: 218-228, 2004. 3. Reid, R., de Silva, M. V. C., Paterson, L., Ryan, E., Fisher, C. Low-grade fibromyxoid sarcoma and hyalinizing spindle cell tumor with giant rosettes share a common t (7;16) (q34; p11) translocation. Am. J. Surg. Path. 27: 1229-1236, 2003.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

57 kDa

6

CAMP responsive element binding protein 3 like 2

Cyclic AMP-responsive element-binding protein 3-like protein 2

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.