Anti-CRISP2 Antilichaam

The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.

Boster Bio Anti-CRISP2 Antibody (Catalog # A10681) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

CT36, TPX1, TSP1, GAPDL5, CRISP-2, Cysteine-rich secretory protein 2, Testis-specific protein TPX-1

CRISP2

P16562

Human

CRISP2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CRISP2. The immunogen is located within the first 50 amino acids of CRISP2.

Testis and epididymis.

ELISA, WB, IHC-P, IF

Signal Transduction

CRISP2 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. .

CRISP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A10681

27259 MW

Cysteine-rich secretory protein 2

Secreted .

Cysteine-rich secretory protein 2

IgG

CRISP2 Antibody is supplied in PBS containing 0.02% sodium azide.