Anti-CRM1 Konijn Monoklonale Antilichaam

Boster Bio Anti-CRM1 Rabbit Monoclonal Antibody catalog # M01180-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Prohibitin; PHB

XPO1

7514

O14980

Human, Mouse, Rat

A synthesized peptide derived from human CRM1 Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP) . Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.

Clone: AEFD-24

Widely expressed in different tissues.

WB, IHC, ICC, IF, Flow Cytometry

Nuclear Receptors, Nuclear Signaling Pathways, Protein Trafficking, RNA Processing, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01180-1

29804 MW

190 kDa

Prohibitin

Mitochondrion inner membrane .

Glycogen synthase kinase-3 beta (gsk3b)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.