Anti-Cullin 1 Monoklonale Antilichaam

Boster Bio Anti-Cullin 1 Monoclonal Antibody catalog # M00658. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Matrix metalloproteinase-14; MMP-14;3.4.24.80; MMP-X1; Membrane-type matrix metalloproteinase 1; MT-MMP 1; MTMMP1; Membrane-type-1 matrix metalloproteinase; MT1-MMP; MT1MMP; MMP14

CUL1

8454

Q13616

Human, Mouse, Rat

A synthesized peptide derived from human Cullin 1 Core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription.

Clone: ADIA-3

Expressed in stromal cells of colon, breast, and head and neck. Expressed in lung tumors. .

WB, IHC, ICC, IF, IP, Flow Cytometry

Apoptosis, Cancer, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Cell Death, Nucleus, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, SCF Complex E3 Ligase, Ubiquitin E3 Enzymes

Affinity-chromatography

0.5mg/ml

Liquid

Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro- MMP2. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00658

65894 MW

44 kDa

Matrix metalloproteinase-14

Membrane ; Single-pass type I membrane protein . Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm.

T-cell surface glycoprotein CD4

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.