Anti-Cytokeratin 5 (C-term) KRT5 Konijn Monoklonale Antilichaam

KRT5 Rabbit Monoclonal Antibody

Keratin, type II cytoskeletal 5;58 kDa cytokeratin; Cytokeratin-5; CK-5; Keratin-5; K5; Type-II keratin Kb5; KRT5

KRT5

3852

P13647

Human, Mouse, Rat

A synthesized peptide derived from human Cytokeratin 5 (C-term)

Clone: AGD-11

Released primarily from activated T lymphocytes.

WB, IHC, ICC, IF

Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53- mediated transcriptional activation. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00398-2

62378 MW

43 kDa

Keratin, type II cytoskeletal 5

Nucleus. Chromosome, centromere, kinetochore. Associated with kinetochores. Both nuclear and cytoplasmic in some cells. Recruited to sites of DNA damage, such as double stand breaks. H4K20me2 is required for efficient localization to double strand breaks and removal of proteins that have a high affinity for H4K20me2 such as L3MBTL1 and KDM4A is needed.

T-cell surface glycoprotein CD4

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.