Anti-D-Dopachrome decarboxylase DDT Antibody Picoband® fluoro647 Vervoeging

DDT, D-dopachrome tautomerization, converts D-dopachrome into 5,6-dihydroxyindole. Northern blot analysis revealed that DDT was expressed as a 0.6-kb mRNA in all tissues tested, with the strongest expression in liver. The DDT gene in human and mouse is identical in exon structure to the MIF gene. Both genes have 2 introns that are located at equivalent positions, relative to a 2-fold repeat in protein structure.the genes for DDT and MIF are closely linked on human chromosome 22 and mouse chromosome 10.

D-dopachrome decarboxylase;4.1.1.84; D-dopachrome tautomerase; Phenylpyruvate tautomerase II; DDT

DDT

1652

P30046

Human, Mouse, Rat

No cross-reactivity with other proteins

E. coli-derived human DDT recombinant protein (Position: M1-L118) .

Flow Cytometry

Cell Biology

Immunogen affinity purified.

Liquid

Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI) .

1. Esumi, N., Budarf, M., Ciccarelli, L., Sellinger, B., Kozak, C. A., Wistow, G.Conserved gene structure and genomic linkage for D-dopachrome tautomerase (DDT) and MIF.Mammalian Genome 9: 753-757, 1998. 2. Nishihira, J., Fujinaga, M., Kuriyama, T., Suzuki, M., Sugimoto, H., Nakagawa, A., Tanaka, I., Sakai, M.Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation.Biochem. Biophys. Res. Commun. 243: 538-544, 1998.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

12712 MW

No cross reactivity with other proteins.

6

D-dopachrome decarboxylase

Cytoplasm .

Belongs to the SCF family.

D-dopachrome decarboxylase

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.