Anti-DCX/Doublecortin Konijn Monoklonale Antilichaam

Boster Bio Anti-DCX/Doublecortin Rabbit Monoclonal Antibody catalog # M01053. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Neuronal migration protein doublecortin; Doublin; Lissencephalin-X; Lis-X; DCX; DBCN, LISX

DCX

1641

O43602

Human, Mouse, Rat

A synthesized peptide derived from human DCX

Clone: AOAD-4

Highly expressed in neuronal cells of fetal brain (in the majority of cells of the cortical plate, intermediate zone and ventricular zone), but not expressed in other fetal tissues. In the adult, highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas.

WB, Flow Cytometry

Cancer, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01053

40574 MW

45 kDa

Neuronal migration protein doublecortin

Cytoplasm. Cell projection . Localizes at neurite tips. .

Glycogen synthase kinase-3 beta (gsk3b)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.