Anti-DEPDC1 Antilichaam (N-term)

Boster Bio Anti-DEPDC1 Antibody (N-term) (Catalog # A08594) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

DEP domain-containing protein 1A, DEPDC1, DEPDC1A

DEPDC1

Q5TB30

Human

This DEPDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-38 amino acids from the N-terminal region of human DEPDC1.

Expressed in testis. Up-regulated in bladder cancer cells (at protein level) .

IHC-P, WB

Cancer

This antibody is purified through a protein A column, followed by peptide affinity purification.

May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A08594

92960 Da

Nucleus. Note=Colocalizes with ZNF224 at the nucleus

Rabbit IgG

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.