Anti-DNAJC10 Antilichaam

Boster Bio Anti-DNAJC10 Antibody catalog # A07954. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.

DnaJ homolog subfamily C member 10;1.8.4.-; Endoplasmic reticulum DNA J domain-containing protein 5; ER-resident protein ERdj5; ERdj5; Macrothioredoxin; MTHr; DNAJC10; ERDJ5; UNQ495/PRO1012

DNAJC10

Q8IXB1

Human, Mouse

Recombinant fusion protein of human DNAJC10 (NP_061854.1) .

WB, ICC, IF

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A07954

91080 MW

DnaJ homolog subfamily C member 10

Endoplasmic reticulum lumen

DnaJ homolog subfamily C member 10

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2