Anti-DNASE2 Antilichaam

DNASE2, or 'acid DNase, ' hydrolyzes DNA under acidic conditions and is one of 2 distinct mammalian DNases. It hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. It has a key role in the degradation of nuclear DNA in cellular apoptosis during development [PMID:18812394]. Besieds, it is necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells. It has been demonstrated to be responsible forDNA degradation in apoptotic cells engulfed by macrophages and exogenous DNA on the skin surface [PMID:23019102]. DNASE2 exists some isoforms with MV 39 and 34 kDa. (PMID: 14644493)

Boster Bio Anti-DNASE2 Antibody catalog # A08512-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.

DNASE2A; DNase II alpha; Deoxyribonuclease-2-alpha; Deoxyribonuclease II alpha; Deoxyribonuclease 2 alpha

DNASE2

O00115

Human, Mouse, Rat

E.coli-derived human DNASE2 recombinant protein (Position: P3-Y358) .

WB, IHC, ICC, IF, IP, ELISA

Immunogen affinity purified.

500 μg/mL

Liquid

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A08512-1

Deoxyribonuclease 2, lysosomal

Deoxyribonuclease-2-alpha

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.