Anti-DP2/TFDP2 Antibody Picoband® fluoro647 Vervoeging

Transcription factor Dp-2 is a protein that in humans is encoded by the TFDP2 gene. The gene is a member of the transcription factor DP family. The encoded protein forms heterodimers with the E2F transcription factors resulting in transcriptional activation of cell cycle regulated genes. Alternative splicing results in multiple transcript variants.

Intraflagellar transport protein 88 homolog; Recessive polycystic kidney disease protein Tg737 homolog; Tetratricopeptide repeat protein 10; TPR repeat protein 10; IFT88; TG737; TTC10

TFDP2

7029

Q14188

Mouse, Rat

No cross-reactivity with other proteins.

A synthetic peptide corresponding to a sequence in the middle region of human DP2/TFDP2, identical to the related mouse sequences.

Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.

Flow Cytometry

Cell Adhesion Proteins, ECM Proteins, Neuroscience

Immunogen affinity purified.

Liquid

Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.

1. Zhang, Y., Chellappan, S. P. Cloning and characterization of human DP2, a novel dimerization partner of E2F. Oncogene 10: 2085-2093, 1995. 2. Zhang, Y., Venkatraj, V. S., Fischer, S. G., Warburton, D., Chellappan, S. P. Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family. Genomics 39: 95-98, 1997.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

104553 MW

6

Intraflagellar transport 88

Centriole. Cilium basal body. Centrosome. Cilium. Cytoplasm. Flagellum.

AP-2 complex subunit beta

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.