Anti-DRAK2 STK17B Antilichaam

Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases) . DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

Boster Bio Anti-DRAK2 STK17B Antibody (Catalog # A08711) . Tested in ELISA, WB, ICC applications. This antibody reacts with Human.

DRAK2, DRAK2, DAP kinase-related apoptosis-inducing protein kinase 2

STK17B

O94768

Human

It has no cross responses to DAP or ZIP kinases. The approximately 70 kDa band is probably non-related to DRAK2 although it is peptide blockable.

DRAK2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human DRAK2. The immunogen is located within the last 50 amino acids of DRAK2.

Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.

ELISA, WB, ICC

Apoptosis, Autophagy

DRAK2 Antibody is Ion exchange chromatography purified.

1 mg/mL

Liquid

Phosphorylates myosin light chains (By similarity) . Acts as a positive regulator of apoptosis.

DRAK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A08711

42344 MW

Serine/threonine kinase 17b

Nucleus

Mouse, Rat

Serine/threonine kinase 17b

IgG

DRAK2 Antibody is supplied in PBS containing 0.02% sodium azide.