Anti-Drebrin DBN1 Konijn Monoklonale Antilichaam

Boster Bio Anti-Drebrin DBN1 Rabbit Monoclonal Antibody catalog # M05530. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Drebrin; Developmentally-regulated brain protein; DBN1; D0S117E

DBN1

1627

Q16643

Human, Mouse, Rat

A synthesized peptide derived from human Drebrin

Clone: ABDC-4

Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas. Expressed in peripheral blood lymphocytes, including T-cells (at protein level) . .

WB, ICC, IF, IP

ECM Proteins, Invasion/Microenvironment, Microfilaments, Neurodegenerative Disease, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites. Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruitment to IS. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M05530

71429 MW

120 kDa

Drebrin

Cytoplasm . Cytoplasm, cell cortex . Cell junction . Cell projection . Cell projection, growth cone . In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC) (PubMed:20215400) . Colocalized with DBN1, RUFY3 and F-actin at the transitional domain of the axonal growth cone (By similarity) . .

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.