Anti-Drosha Konijn Monoklonale Antilichaam

Boster Bio Anti-Drosha Rabbit Monoclonal Antibody catalog # M00111. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Ribonuclease 3;3.1.26.3 ; Protein Drosha ; Ribonuclease III; RNase III; p241; DROSHA; RN3, RNASE3L, RNASEN

DROSHA

29102

Q9NRR4

Human

A synthesized peptide derived from human Drosha

Clone: ABEF-4

Ubiquitous. .

WB, IHC, ICC, IF, Flow Cytometry

2339, DNA/RNA, Epigenetics and Nuclear Signaling, Nuclear Receptors, Nuclear Signaling Pathways, RNA Processing

Affinity-chromatography

0.5mg/ml

Liquid

Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA- ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double- strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00111

159316 MW

159 kDa

Ribonuclease 3

Nucleus . Nucleus, nucleolus . A fraction is translocated to the nucleolus during the S phase of the cell cycle. Localized in GW bodies (GWBs), also known as P-bodies. .

P2X purinoceptor 1

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.