Anti-E2F1 Konijn Monoklonale Antilichaam

Boster Bio Anti-E2F1 Rabbit Monoclonal Antibody catalog # M00257. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Transcription factor E2F1; E2F-1; PBR3; Retinoblastoma-associated protein 1; RBAP-1; Retinoblastoma-binding protein 3; RBBP-3; pRB-binding protein E2F-1; E2F1; RBBP3

E2F1

1869

Q01094

Human, Mouse, Rat

A synthesized peptide derived from human E2F1

Clone: IGD-5

Ubiquitous, with higher levels in heart, pancreas and testis, and lower levels in kidney and brain.

WB, IHC, ICC, IF, IP, Flow Cytometry

Cancer, Domain Families, Epigenetics and Nuclear Signaling, Forkhead Box, Oncoproteins/Suppressors, Transcription, Tumor Suppressors

Affinity-chromatography

0.5mg/ml

Liquid

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00257

46920 MW

34 kDa

Transcription factor E2F1

Nucleus.

P2X purinoceptor 1

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.