Anti-EIF2C3 AGO3 Konijn Monoklonale Antilichaam

Boster Bio Anti-EIF2C3 AGO3 Rabbit Monoclonal Antibody catalog # M04191. Tested in IHC, WB application. This antibody reacts with Human, Mouse, Rat.

Protein argonaute-3 ; Argonaute3 ; hAgo3; Argonaute RISC catalytic component 3; Eukaryotic translation initiation factor 2C 3 ; eIF-2C 3 ; eIF2C 3 ; AGO3; EIF2C3

AGO3

192669

Q9H9G7

Human, Mouse, Rat

A synthesized peptide derived from human EIF2C3

Clone: GGF-1

Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. .

WB, IHC

DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing

Affinity-chromatography

0.5mg/ml

Liquid

Required for RNA-mediated gene silencing (RNAi) . Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M04191

97360 MW

70 kDa

Protein argonaute-3

Cytoplasm, P-body .

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.