Anti-FAA/FAH Antibody Picoband® fluoro647 Vervoeging

Fumarylacetoacetase is an enzyme that in humans is encoded by the FAH gene located on chromosome 15. The FAH gene is thought to be involved in the catabolism of the amino acid phenylalanine in humans. This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT) .

Deleted in azoospermia-like; DAZ homolog; DAZ-like autosomal; Deleted in azoospermia-like 1; SPGY-like-autosomal; DAZL; DAZH; DAZL1; DAZLA; SPGYLA

FAH

2184

P16930

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human FAA/FAH recombinant protein (Position: M1-P342) .

Flow Cytometry

Angiogenesis, Cancer, Cardiovascular, Cytokines, Immunology, Innate Immunity, Interleukins, Invasion/Microenvironment

Immunogen affinity purified.

Liquid

RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts.

1. Berube, D., Phaneuf, D., Tanguay, R. M., Gagne, R. Assignment of the fumarylacetoacetate hydrolase gene to chromosome 15q23-15q25. (Abstract) Cytogenet. Cell Genet. 51: 962 only, 1989. 2. Demers, S. I., Phaneuf, D., Tanguay, R. M. Hereditary tyrosinemia type I: strong association with haplotype 6 in French Canadians permits simple carrier detection and prenatal diagnosis. Am. J. Hum. Genet. 55: 327-333, 1994. 3. Grompe, M., Al-Dhalimy, M. Mutations of the fumarylacetoacetate hydrolase gene in four patients with tyrosinemia, type I. Hum. Mutat. 2: 85-93, 1993.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Deleted in azoospermia like

Nucleus. Cytoplasm.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.