Anti-Factor VII/F7 Antibody Picoband® fluoro488 Vervoeging

Reporter gene

Coagulation factor VII;3.4.21.21; Proconvertin; Serum prothrombin conversion accelerator; SPCA; Eptacog alfa; Factor VII light chain; Factor VII heavy chain; F7

F7

2155

P08709

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human Factor VII.

Plasma.

Flow Cytometry

Cell Type Markers, Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Signal Transduction, Tags & Cell Markers, Tumor Associated

Immunogen affinity purified.

Liquid

Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.

1. Di Bitondo, R., Hall, A. J., Peake, I. R., Iacoviello, L., Winship, P. R. Oestrogenic repression of human coagulation factor VII expression mediated through an oestrogen response element sequence motif in the promoter region. Hum. Molec. Genet. 11: 723-731, 2002. 2. Millar, D. S., Kemball-Cook, G., McVey, J. H., Tuddenham, E. G. D., Mumford, A. D., Attock, G. B., Reverter, J. C., Lanir, N., Parapia, L. A., Reynaud, J., Meili, E., von Felton, A., Martinowitz, U., Prangnell, D. R., Krawczak, M., Cooper, D. N. Molecular analysis of the genotype-phenotype relationship in factor VII deficiency. Hum. Genet. 107: 327-342, 2000. 3. Zur, M., Nemerson, Y. Tissue factor pathways of blood coagulation.In: Bloom, A. L.; Thomas, D. P. : Haemostasis and thrombosis. Edinburgh: Churchill Livingstone (pub.) 1981.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

51594 MW

No cross reactivity with other proteins.

6

Coagulation factor VII

Secreted.

Belongs to the peptidase S1 family.

Coagulation factor VII

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.