Anti-FATP4/SLC27A4 Antibody Picoband® fluoro647 Vervoeging

Long-chain fatty acid transport protein 4 is a protein that in humans is encoded by the SLC27A4 gene. This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome.

Loricrin; LOR; LRN

SLC27A4

10999

Q6P1M0

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human FATP4/SLC27A4 recombinant protein (Position: K15-L643) .

Expressed in testis and to a lesser degree in brain, ovary and placenta. Found in most tissues at low levels.

Flow Cytometry

Cell Biology, Cytokines, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, Interferons, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers, Ubiquitin E3 Enzymes

Immunogen affinity purified.

Liquid

Major keratinocyte cell envelope protein.

1. Esperon-Moldes, U. S., Ginarte, M., Santamarina, M., Rodriguez-Lage, B., Rodriguez-Pazos, L., Vega, A. Novel compound heterozygous FATP4 mutations caused ichthyosis prematurity syndrome in Spanish sisters. Acta Paediat. 108: 763-765, 2019. 2. Gertow, K., Bellanda, M., Eriksson, P., Boquist, S., Hamsten, A., Sunnerhagen, M., Fisher, R. M. Genetic and structural evaluation of fatty acid transport protein-4 in relation to markers of the insulin resistance syndrome. J. Clin. Endocr. Metab. 89: 392-399, 2004. 3. Hirsch, D., Stahl, A., Lodish, H. F. A family of fatty acid transporters conserved from mycobacterium to man. Proc. Nat. Acad. Sci. 95: 8625-8629, 1998.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

39411 MW

6

Loricrin

Nucleoplasm. Cytoplasm.

Zinc finger protein Helios

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.