Anti-Fibroblast groeifactor 9 FGF9 Antibody Picoband® fluoro488 Vervoeging

FGF 9, Fibroblast growth factor 9, is a protein that in humans is encoded by the FGF9 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF 9 gene contains 3 exons. By radioactive chromosomal in situ hybridization, the FGF 9 gene is mapped to chromosome 13q11-q12. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling.

Fibroblast growth factor 9; FGF-9; Glia-activating factor; GAF; Heparin-binding growth factor 9; HBGF-9; FGF9

FGF9

2254

P31371

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence in the middle region of human FGF9, identical to the related mouse and rat sequences.

Glial cells.

Flow Cytometry

Angiogenesis, Cardiovascular, Developmental Biology, Growth Factors, Growth Factors/Hormones, Neurogenesis, Neurology Process, Neuroscience, Reproduction, Signal Transduction

Immunogen affinity purified.

Liquid

Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. .

1. Mariani, F. V., Ahn, C. P., Martin, G. R.Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning.Nature 453: 401-405, 2008. 2. Mattei, M.-G., Penault-Llorca, F., Coulier, F., Birnbaum, D.The human FGF 9 gene maps to chromosomal region 13q11-q12.Genomics 29: 811-812, 1995. 3. Sun, X., Lewandoski, M., Meyers, E. N., Liu, Y.-H., Maxson, R. E., Jr., Martin, G. R.Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development.Nature Genet. 25: 83-86, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

23441 MW

No cross reactivity with other proteins.

6

Fibroblast growth factor 9

Secreted.

Belongs to the heparin-binding growth factors family.

Fibroblast growth factor 9 (FGF-9)

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.