Anti-FMRP FMR1 Konijn Monoklonale Antilichaam

Boster Bio Anti-FMRP FMR1 Rabbit Monoclonal Antibody catalog # M00192. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Fragile X mental retardation protein 1; FMRP; Protein FMR-1; FMR1

FMR1

2332

Q06787

Human, Mouse, Rat

A synthesized peptide derived from human FMRP

Clone: ABAA-6

Highest levels found in neurons, brain, testis, placenta and lymphocytes. Also expressed in epithelial tissues and at very low levels in glial cells. .

WB, IHC, ICC, IF

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling, Neural Signal Transduction, Neurology Process, Neuroscience

Affinity-chromatography

0.5mg/ml

Liquid

Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity) . RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly (G), binds moderately to poly (U) but shows very little binding to poly (A) or poly (C) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00192

71174 MW

40 kDa

Fragile X mental retardation protein 1

Cytoplasm . Nucleus . Nucleus, nucleolus .

P2X purinoceptor 1

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.