Anti-FXR2 Antibody Picoband®

Fragile X mental retardation syndrome-related protein 2 is a protein that in humans is encoded by the FXR2 gene. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome.

Boster Bio Anti-FXR2 Antibody Picoband® catalog # A05130-4. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Sodium- and chloride-dependent GABA transporter 1; GAT-1; Solute carrier family 6 member 1; SLC6A1; GABATR, GABT1, GAT1

FXR2

9513

P51116

Human, Monkey, Mouse

No cross-reactivity with other proteins.

E.coli-derived human FXR2 recombinant protein (Position: N153-K651) .

Expressed in many tissues, highest levels in skeletal muscle.

WB, Flow Cytometry, ELISA

Neuroscience, Neurotransmitter, Transporters

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

1. Bontekoe, C. J. M., McIlwain, K. L., Nieuwenhuizen, I. M., Yuva-Paylor, L. A., Nellis, A., Willemsen, R., Fang, Z., Kirkpatrick, L., Bakker, C. E., McAninch, R., Cheng, N. C., Merriweather, M., Hoogeveen, A. T., Nelson, D., Paylor, R., Oostra, B. A. Knockout mouse model for Fxr2: a model for mental retardation. Hum. Molec. Genet. 11: 487-498, 2002. 2. Darnell, J. C., Fraser, C. E., Mostovetsky, O., Darnell, R. B. Discrimination of common and unique RNA-binding activities among fragile X mental retardation protein paralogs. Hum. Molec. Genet. 18: 3164-3177, 2009. 3. Kirkpatrick, L. L., McIlwain, K. A., Nelson, D. L. Comparative genomic sequence analysis of the FXR gene family: FMR1, FXR1, and FXR2. Genomics 78: 169-177, 2001.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A05130-4

67074 MW

93 kDa

6

Sodium- and chloride-dependent GABA transporter 1

Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons (By similarity) . .

Long-chain-fatty-acid--CoA ligase 5

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.