Anti-Gastrotropin FABP6 Antibody Picoband® fluoroc647 Vervoeging

Fatty acid binding protein 6, ileal, also called FABP6 or ILBP is a protein which in humans is encoded by the FABP6 gene. Ileal lipid-binding protein (ILBP) is a member of a family of intracellular fatty acid, retinoid, and bile acid-binding proteins. This gene is mapped to 5q33.3. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is though that FABPs roles include fatty acid uptake, transport, and metabolism.

Gastrotropin; GT; Fatty acid-binding protein 6; Ileal lipid-binding protein; ILBP; Intestinal 15 kDa protein; I-15P; Intestinal bile acid-binding protein; I-BABP; FABP6; ILBP, ILLBP

FABP6

2172

P51161

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the N-terminus of human FABP6.

Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level) . Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. .

Flow Cytometry

Cancer, Cancer Metabolism, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism of Lipids and Lipoproteins, Pathways and Processes, Signal Transduction, Tumor Biomarkers

Immunogen affinity purified.

Liquid

Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis. .

1. Birkenmeier, E. H., Rowe, L. B., Crossman, M. W., Gordon, J. I. Ileal lipid-binding protein (Illbp) gene maps to mouse chromosome 11. Mammalian Genome 5: 805-806, 1994. 2. Oelkers, P., Dawson, P. A. Cloning and chromosomal localization of the human ileal lipid-binding protein. Biochim. Biophys. Acta 1257: 199-202, 1995.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

14371 MW

No cross reactivity with other proteins.

6

Gastrotropin

Isoform 1: Cytoplasm.

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Gastrotropin

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.