Anti-GBP1 Antibody Picoband®

Interferon-induced guanylate-binding protein 1 is a protein that in humans is encoded by the GBP1 gene. It belongs to the dynamin superfamily of large GTPases. Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.

Boster Bio Anti-GBP1 Antibody Picoband® catalog # A03067-1. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

GBP1

2633

P32455

Human, Mouse, Rat

E.coli-derived human GBP1 recombinant protein (Position: E190-S592) .

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

1. Cheng, Y.-S. E., Patterson, C. E., Staeheli, P. Interferon-induced guanylate-binding proteins lack an N (T) KXD consensus motif and bind GMP in addition to GDP and GTP. Molec. Cell. Biol. 11: 4717-4725, 1991. 2. Gaudet, R. G., Zhu, S., Halder, A., Kim, B.-H., Bradfield, C. J., Huang, S., Xu, D., Maminska, A., Nguyen, T. N., Lazarou, M., Karatekin, E., Gupta, K., MacMicking, J. D. A human apolipoprotein L with detergent-like activity kills intracellular pathogens. Science 373: eabf8113, 2021. 3. Ghosh, A., Praefcke, G. J. K., Renault, L., Wittinghofer, A., Herrmann, C. How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. Nature 440: 101-104, 2006.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A02111-21

68 kDa

68 kDa

6

IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.