Anti-Gem-geassocieerde proteïne 8 GEMIN8 Antilichaam

Boster Bio Anti-Gem-associated protein 8 GEMIN8 Antibody catalog # A11881. Tested in WB applications. This antibody reacts with Human.

Gem-associated protein 8; Gemin-8; Protein FAM51A1; GEMIN8; FAM51A1

GEMIN8

Q9NWZ8

Human

Recombinant fusion protein of human GEMIN8 (NP_060326.1) .

WB

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A11881

28637 MW

WB: 1:500-1:2000

Gem-associated protein 8

Nucleus, gem

Gem-associated protein 8

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2