Anti-GGA2 Antibody Picoband® 31.0550 Vervoeging

ADP-ribosylation factor-binding protein GGA2 is a protein that in humans is encoded by the GGA2 gene. ADP-ribosylation factor-binding protein GGA2 is a protein that in humans is encoded by the GGA2 gene. This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.

GGA2

23062

Q9UJY4

Human

E.coli-derived human GGA2 recombinant protein (Position: L26-A608) . Human GGA2 shares 85.4% amino acid (aa) sequence identity with mouse GGA2.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Dell'Angelica, E. C., Puertollano, R., Mullins, C., Aguilar, R. C., Vargas, J. D., Hartnell, L. M., Bonifacino, J. S. GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex. J. Cell Biol. 149: 81-93, 2000. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 2/23/2017. 3. Hirst, J., Lui, W. W. Y., Bright, N. A., Totty, N., Seaman, M. N. J., Robinson, M. S. A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome. J. Cell Biol. 149: 67-69, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.