Anti-Glucagon Gcg Antilichaam (Monoclonal, K79bB10)

Glucagon is a member of a multigene family that includes secretin. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. The human glucagon gene is approximately 9.4 kb long and contains 6 exons and 5 introns, and assigned to 2q36-2q37.

Boster Bio Anti-Glucagon Gcg Antibody (Monoclonal, K79bB10) catalog # MA1047. Tested in IF, IHC applications. This antibody reacts with Human, Mouse, Rabbit, Rat.

Glucagon; Glicentin; Glicentin-related polypeptide; GRPP; Oxyntomodulin; OXM; OXY; Glucagon; Glucagon-like peptide 1; GLP-1; Glucagon-like peptide 1 (7-37) ; GLP-1 (7-37) ; Glucagon-like peptide 1 (7-36) ; GLP-1 (7-36) ; Glucagon-like peptide 2; GLP-2; Gcg

GCG

Human (2641), Mouse (14526), Rat (24952)

P06883

Human, Mouse, Rabbit, Rat

No cross-reactivity with other proteins

Polymerized porcine glucagon.

Clone: K79bB10

Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. .

IF, IHC

Cancer, Cancer Metabolism, Developmental Biology, Energy Transfer Pathways, Growth Factors/Hormones, Integration Of Energy, Integration Of Energy Metabolism, Lineage Markers, Lineage Specification, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Stem Cells, Tumor Biomarkers

Ascites

Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Lyophilized

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. .

1. Schroeder, W. T.; Lopez, L. C.; Harper, M. E.; Saunders, G. F. : Localization of the human glucagon gene (GCG) to chromosome segment 2q36-37. Cytogenet. Cell Genet. 38: 76-79, 1984. 2. White, J. W.; Saunders, G. F. : Structure of the human glucagon gene. Nucleic Acids Res. 14: 4719-4730, 1986.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=MA1047

20846 MW

50 kDa

No cross reactivity with other proteins.

Glucagon

Secreted.

Belongs to the glucagon family.

Glucagon

Mouse IgG1

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.