Anti-glutaredoxin 1/GLRX Antibody Picoband®

Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene. This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Boster Bio Anti-Glutaredoxin 1/GLRX Antibody Picoband® catalog # A03392-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Vitamin D-binding protein; DBP; VDB; Gc-globulin; Group-specific component; Gc

GLRX

2745

P35754

Human

No cross-reactivity with other proteins.

E.coli-derived human Glutaredoxin 1/GLRX recombinant protein (Position: M1-Q106) .

ELISA, Flow Cytometry, IF, IHC, ICC, WB

Actin Binding Proteins, Actin, etc., Cancer, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction, Tumor Antigens, Tumor Biomarkers, Tumor Immunology, Tumor-Associated Antigens

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.

1. Padilla, C. A., Bajalica, S., Lagercrantz, J., Holmgren, A. The gene for human glutaredoxin (GLRX) is localized to human chromosome 5q14. Genomics 32: 455-457, 1996. 2. Padilla, C. A., Martinez-Galisteo, E., Barcena, J. A., Spyrou, G., Holmgren, A. Purification from placenta, amino acid sequence, structure comparisons and cDNA cloning of human glutaredoxin. Europ. J. Biochem. 227: 27-34, 1995. 3. Raghavachari, N., Krysan, K., Xing K., Lou, M. F. Regulation of thioltransferase expression in human lens epithelial cells. Invest. Ophthal. Vis. Sci. 42: 1002-1008, 2001.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A03392-1

12 kDa

6

Group specific component

Secreted.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.