Anti-glutathionperoxidase 1 (GPx-1) Antilichaam

Glutathione peroxidase 1 has a role in detoxification of hydrogen peroxide and is one of the most important antioxidant enzymes in humans. It exists as a homotetramer which localises to the cytoplasm. It belongs to the glutathione peroxidase family. Glutathione peroxidase 1 is one of few proteins in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. This protein has a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine repeats. The allele with five alanine repeats is significantly associated with breast cancer risk. At least two alternatively spliced isoforms have been identified.

Our Anti-Glutathione peroxidase 1 (GPx-1) rabbit polyclonal primary antibody detects human and rat Glutathione peroxidase 1 (GPx-1), and is whole serum. It is validated for use in ELISA, IHC-Paraffin-embedded, WB.

Our Anti-Glutathione peroxidase 1 (GPx-1) rabbit polyclonal primary antibody detects human and rat Glutathione peroxidase 1 (GPx-1), and is whole serum. It is validated for use in ELISA, IHC-Paraffin-embedded, WB.

Glutathione peroxidase 1; GPx-1; GSHPx-1; Cellular glutathione peroxidase; GPX1

P07203

Human and Rat

A synthetic peptide (RRYSRRFQTIDIEPDIEALL) corresponding to the amino acids 175-194 of human glutathione peroxidase 1 (GPx-1) conjugated to diphtheria toxin has been used as the immunogen.

Glutathione peroxidase 1 (GPx-1)

Unconjugated

ELISA, IHC-Paraffin-embedded, WB

Whole serum

Lyophilized serum with 0.02% thimerosal

22 kDa (see application details)

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. At least 12 months after purchase at 2-8°C (lyophilized formulations) . After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.

1:200-1:1000

1:1000-1:2000

Human and rat cellular selenium dependent glutathione peroxidase. Human; rat; .

Rabbit

Lyophilized

Mixed

Human