Anti-GMPPB Antilichaam

GMPPB is a cytoplasmic enzyme that catalyzes the formation of GDP-mannose, a key substrate for several glycosylation pathways, including O-mannosylation of α-DG. GMPPB facilitates the formation of the sugar donor GDP-mannose and pyrophosphate from mannose-1-phosphate and GTP, a very early step in the glycosylation pathway (PMID: 37834154, 27147698) . GMPPB mutations correlate with several congenital diseases, including severe congenital muscular dystrophy (CMD) with abnormalities in the brain and eye (PMID: 26310427, 30684953) . Western blot analysis detected GMPPB at an apparent molecular mass of 40 kDa.

Boster Bio Anti-GMPPB Antibody catalog # A08665. Tested in WB, IHC, ICC/IF, ELISA. This antibody reacts with Human, Mouse, Rat.

GMPPB

Q9Y5P6

Human, Mouse, Rat

E.coli-derived human GMPPB recombinant protein (Position: A3-R357) .

WB, IHC, ICC/IF, ELISA

Immunogen affinity purified.

500 μg/mL

Liquid

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

https://www.bosterbio.com/datasheet?sku=A08665

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.