Anti-GNL3L Antilichaam

Boster Bio Anti-GNL3L Antibody catalog # A09415. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat, Cat.

Guanine nucleotide-binding protein-like 3-like protein; GNL3L

GNL3L

Q9NVN8

Human, Mouse, Rat, Cat

The antiserum was produced against synthesized peptide derived from human GNL3L. AA range:71-120

WB, IHC, IF, ELISA

Immunogen affinity purified

1 mg/mL

Liquid

Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09415

65573 MW

Guanine nucleotide-binding protein-like 3-like protein

Nucleus, nucleolus .

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.