Anti-Golgin 97/GOLGA1 Antibody Picoband® fluoro647 Vervoeging

Golgin subfamily A member 1 is a protein that in humans is encoded by the GOLGA1 gene. The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs) . Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein is associated with Sjogren's syndrome.

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

GOLGA1

2800

Q92805

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human Golgin 97/GOLGA1 recombinant protein (Position: M1-K752) .

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Flow Cytometry

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Immunogen affinity purified.

Liquid

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

1. Griffith, K. J., Chan, E. K. L., Lung, C.-C., Hamel, J. C., Guo, X., Miyachi, K., Fritzler, M. J. Molecular cloning of a novel 97-Kd Golgi complex autoantigen associated with Sjogren's syndrome. Arthritis Rheum. 40: 1693-1702, 1997. 2. Lu, L., Tai, G., Hong, W. Autoantigen golgin-97, an effector of Arl1 GTPase, participates in traffic from the endosome to the trans-Golgi network. Molec. Biol. Cell 15: 4426-4443, 2004. 3. Wong, M., Munro, S. The specificity of vesicle traffic to the Golgi is encoded in the golgin coiled-coil proteins. Science 346: 1256898, 2014. Note: Electronic Article.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

64099 MW

6

RNA-binding protein 47

Nucleus .

Follicular dendritic cell secreted peptide

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.